Article
Identification of cytotoxic T cell epitopes on the VP3 and VP6 rotavirus proteins.
The Journal of general virology - 1 Mar 1994
Franco M A, Lefevre P, Willems P, Tosser G, Lintermanns P, Cohen J
Abstract excerpt
It has been shown previously that the viral glycoprotein VP7 is a major target of cytotoxic T lymphocytes (CTLs) induced by bovine rotavirus RF in C57BL/6 mice. Here we show that these RF-specific CTLs recognize target cells infected with a recombinant vaccinia virus (rVV) expressing the SA11 (simian rotavirus) VP6 but not those infected with rVVs that express RF VP1, VP2 or VP3 core proteins. After immunization...
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