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Article

Reduction of a conserved Cys is essential for Myb DNA-binding.

Nucleic acids research - 11 May 1992

Guehmann S, Vorbrueggen G, Kalkbrenner F, Moelling K

Abstract excerpt

The human c-Myb gene product is a regulator of transcription with intrinsic DNA-binding activity located in two of three aminoterminal repeats R2R3. Three purified recombinant c-Myb proteins, a 42 kD protein corresponding to the amino-terminal half (HM42), and two proteins representing R2R3 or R1R2R3 (HMR23 and HMR123) have been analyzed either as purified proteins or present in bacterial extracts in gelshift...

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Identifiers

PMID: 1594446
DOI: 10.1093/nar/20.9.2279
PMCID: PMC312342

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Reduction of a conserved Cys is essential for Myb DNA-binding.PMID 1594446Read ↗

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Crystallization and preliminary X-ray analysis of wild-type and V103L mutant Myb R2 DNA-binding domain.Semantic proximity Read ↗

Construction of an artificial tandem protein of the c-Myb DNA-binding domain and analysis of its DNA binding specificity.Semantic proximity Read ↗

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