Article
Clinical implications of pharmacokinetics and pharmacodynamics of fluoroquinolones.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Jul 2005
Wispelwey Brian
Abstract excerpt
This review summarizes key data illustrating the clinical importance of pharmacodynamics, particularly among the fluoroquinolone family of antibacterials. Antibacterials are often divided into 2 groups--either time-dependent or concentration-dependent agents--on the basis of their mechanism of killing. Fluoroquinolones are concentration-dependent agents, and the parameter that correlates most closely with...
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