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Article

Fluoroquinolone pharmacodynamics: prospective determination of relationships between exposure and outcome.

Journal of chemotherapy (Florence, Italy) - 1 Oct 2000

Drusano G L

Abstract excerpt

By using mathematical modeling it is possible to determine relationships between drug exposure and clinical or microbiological outcome. From the early exploration of Pseudomonas aeruginosa sepsis in neutropenic rats to the prospective determination of relationships between fluoroquinolone exposure and patient outcome in multicenter clinical trials, the utility of this approach has been confirmed. This prospective...

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Identifiers

PMID: 11131956
DOI: 10.1080/1120009x.2000.11782309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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