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Article

Towards the genetic analysis of mulfactorial diseases: the estimation of allele frequency and epistasis.

Human heredity - 1 Jan 2002

Stewart John

Abstract excerpt

OBJECTIVES: The general aim of this paper is to reactivate the original intention behind the Elston-Stewart algorithm: i.e. physiological characterisation of the effects of individual loci underlying quantitative variation. The specific aim is the estimation of allele frequency and epistasis in multifactorial genetic diseases. METHODS: In a general genetic model, the probability of disease is a sigmoid function...

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Identifiers

PMID: 12626845
DOI: 10.1159/000068837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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