Article
[Ultrastructure and crystallin mutant molecular modeling of hereditary coralliform cataract].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 1 May 2005
Xu Wei-zhen, Zheng Shu, Dong Qi, Cai Shan-rong, Yao Ke, Zhang Su-zhan
Abstract excerpt
OBJECTIVE: To observe the correlation of gammaD-crystallin P23T mutant with lens ultrastructure of the hereditary coralliform cataract. METHODS: Complete ophthalmologic examinations were performed before lens extraction and lens samples were studied by transmission and scanning electric microscope respectively. Protein molecular modeling was performed using SWISS-MODEL(version 2.0). RESULTS: Protein structure...
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