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Article

Impaired expression of myogenic regulatory molecules in the pelvic floor muscles of murine embryos with anorectal malformations.

Journal of pediatric surgery - 1 May 2005

Aoi Shigeyoshi, Shimotake Takashi, Tsuda Tomoki, Deguchi Eiichi, Iwai Naomi

Abstract excerpt

BACKGROUND/PURPOSE: Recent biological studies have elucidated the molecular mechanism of muscle development, in which various regulatory factors (myogenic regulatory factors [MRFs]) play key roles during embryogenesis. To investigate the development of anorectal malformations (ARMs), we studied MRF expressions in myogenic cells in the pelvic floor using murine embryos affected with ARM. METHODS: Anorectal...

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Identifiers

PMID: 15937819
DOI: 10.1016/j.jpedsurg.2005.01.047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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