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Article

Genetic predictors for drug resistance in soft tissue sarcoma: a review of publications in 2004.

Current opinion in oncology - 1 Jul 2005

Fayette Jérôme, Blay Jean-Yves

Abstract excerpt

PURPOSE OF REVIEW: Sarcomas are generally managed through a multidisciplinary approach including surgery, radiotherapy, and chemotherapy. Metastatic tumor cells frequently develop resistance to cytotoxic agents. Several molecular mechanisms of drug resistance have been uncovered recently. RECENT FINDINGS: Among genes governing the apoptosis pathway, overexpression of the bcl2 family or mutations of p53 have...

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Identifiers

PMID: 15933471
DOI: 10.1097/01.cco.0000166650.30793.f2

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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