Article
The adult pituitary contains a cell population displaying stem/progenitor cell and early embryonic characteristics.
Endocrinology - 1 Sept 2005
Chen Jianghai, Hersmus Nicole, Van Duppen Vik, Caesens Pieter, Denef Carl, Vankelecom Hugo
Abstract excerpt
A side population (SP) has been identified in a number of tissues, where it typically represents a small population enriched in stem/progenitor cells. In this study we show that the adult mouse anterior pituitary (AP) also contains a characteristic SP displaying verapamil-sensitive Hoechst dye efflux capacity. A majority of the SP cells express stem cell antigen 1 at a high level (Sca1high). Using...
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