Article
Distinct population of hair cell progenitors can be isolated from the postnatal mouse cochlea using side population analysis.
Stem cells (Dayton, Ohio) - 1 Feb 2007
Savary Etienne, Hugnot Jean Philippe, Chassigneux Yolaine, Travo Cecile, Duperray Christophe, Van De Water Thomas, Zine Azel
Abstract excerpt
In mammals, the permanence of hearing loss is due mostly to the incapacity of the cochlea to replace lost mechano-receptor cells (i.e., hair cells [HCs]). The generation of new HCs from a renewable source of progenitors is a principal requirement for developing a cell therapy within this sensory organ. A subset of stem cells, termed side population (SP), has been identified in several tissues of mammals. The...
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