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Article

Ribosome display of mammalian receptor domains.

Protein engineering, design & selection : PEDS - 1 Jun 2005

Schimmele Bernhard, Gräfe Nico, Plückthun Andreas

Abstract excerpt

Many mammalian receptor domains, among them a large number of potential therapeutic target proteins, are highly aggregation-prone upon heterologous expression in bacteria. This severely limits functional studies of such receptor domains and also their engineering towards improved properties. One of these proteins is the Nogoreceptor, which plays a central role in mediating the inhibition of axon growth and...

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PMID: 15932906
DOI: 10.1093/protein/gzi030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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