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In Vitro Selection of Peptides and Proteins—Advantages of mRNA Display

31 Dec 2019

Abstract excerpt

mRNA display is a robust in vitro selection technique that allows the selection of peptides and proteins with desired functions from libraries of trillions of variants. mRNA display relies upon a covalent linkage between a protein and its encoding mRNA molecule; the power of the technique stems from the stability of this link, and the large degree of control over experimental conditions afforded to the...

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PMID: 31891492
DOI: 10.1021/acssynbio.9b00419

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