Article
Detection of a new 3-base pair insertion mutation in the protease gene of human immunodeficiency virus type 1 during highly active antiretroviral therapy (HAART).
AIDS research and human retroviruses - 1 May 2005
Tramuto Fabio, Bonura Filippa, Mancuso Salvatrice, Romano Nino, Vitale Francesco
Abstract excerpt
To investigate a new insertion mutation in the protease (PR) gene of human immunodeficiency virus type 1 (HIV-1) in a patient extensively pretreated with antiretroviral drugs, genotypic analyses of plasma-derived viruses were performed by sequencing segments of 1302 nucleotides in the pol gene of...
Topics
- Adult
- Antiretroviral Therapy, Highly Active
- Base Pairing
- Base Sequence
- Codon
- Female
- Gene Products, pol
- HIV Infections
- HIV Protease
- HIV-1
- Humans
- Molecular Sequence Data
- Mutation
- Sequence Analysis, DNA