Article
Long-term follow-up of 11 protease inhibitor (PI)-naïve and PI-treated HIV-infected patients harbouring virus with insertions in the HIV-1 protease gene.
HIV medicine - 1 Mar 2011
Amiel C, Charpentier C, Désiré N, Bonnard P, Lebrette M-G, Weiss L, Pialoux G, Schneider V
Abstract excerpt
OBJECTIVES: Amino acid insertions in the protease gene have been reported rarely, and mainly in patients receiving protease inhibitors (PIs). The aim of the study was to assess the long-term viro-immunological follow-up of HIV-infected patients harbouring virus with protease insertions. METHODS: Cases of virus exhibiting protease insertions were identified in routine resistance genotyping tests. Therapeutic,...
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