Article
Neurosteroids exhibit differential effects on mIPSCs recorded from normal and seizure prone rats.
Journal of neurophysiology - 1 Sept 2005
Schwabe Kerstin, Gavrilovici Cezar, McIntyre Dan C, Poulter Michael O
Abstract excerpt
In the perirhinal cortex of seizure prone (SP) rats, GABA(A)-mediated miniature inhibitory postsynaptic currents (mIPSCs) are smaller in amplitude but have longer deactivation phases than mIPSCs recorded in normal control (NC; outbred) rats. These differences in mIPSCs are correlated to the relatively higher alpha1 subunit expression in the NC rat strains and the higher alpha2, alpha3, and alpha5 subunit...
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