Article
Effects of serotonin on induced epileptiform activity in CA1 pyramidal neurons of genetically epilepsy prone rats.
Brain research - 16 Dec 1996
Salgado-Commissariat D, Alkadhi K A
Abstract excerpt
The seizure susceptibility in genetically epilepsy prone rats (GEPRs) is reported to be caused by abnormalities in several neurotransmitter systems including the serotonergic system. Among the reported abnormalities is a decrease in brain serotonin content. Therefore, we examined the effects of exogenous serotonin on brain slices from the severe seizure strain of GEPRs (GEPR-9s). We employed conventional...
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