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Article

Spectrum of germ-line MLH1 and MSH2 mutations in Austrian patients with hereditary nonpolyposis colorectal cancer.

Wiener klinische Wochenschrift - 1 Apr 2005

Wolf Brigitte, Henglmueller Silvia, Janschek Elisabeth, Ilencikova Denisa, Ludwig-Papst Carmen, Bergmann Michael, Mannhalter Christine, Wrba Friedrich, Karner-Hanusch Judith

Abstract excerpt

BACKGROUND: Germ-line mutations in mismatch repair genes are associated with the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome, which is characterized by susceptibility to cancer of the colon, endometrium, small bowel or urothelium at an unusually young age and with a high degree of penetration in all generations. MATERIAL AND METHODS: One hundred and nine individuals from 46 Austrian families who...

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Source

Identifiers

PMID: 15926618
DOI: 10.1007/s00508-005-0337-8

Genes

MLH1
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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