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Article

PU.1-mediated transcriptional regulation of prophenin-2 in primary bone marrow cells.

Gene - 6 Jun 2005

Ramanathan Balaji, Minton J Ernest, Ross Chris R, Blecha Frank

Abstract excerpt

Prophenin-2 (PF-2) is a cathelicidin, 97-amino-acid antimicrobial protein stored in neutrophil secondary granules. PF-2 is expressed specifically in porcine immature myeloid cells; however, little is known about its regulation. In this study, we characterized the 5' regulatory regions of the PF-2 gene to understand the molecular mechanisms regulating its expression. Using bioinformatic approaches, site-directed...

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Identifiers

PMID: 15922520
DOI: 10.1016/j.gene.2005.04.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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