Article
Molecular characterization and chromosome assignment of the porcine gene for leukemia inhibitory factor LIF.
Cytogenetics and cell genetics - 1 Jan 2001
Spötter A, Drögemüller C, Kuiper H, Brenig B, Leeb T, Distl O
Abstract excerpt
Leukemia inhibitory factor (LIF) is a pleiotropic cytokine involved in early conceptus development in pig. We isolated a PAC clone containing the porcine LIF gene and determined the complete DNA sequence of the gene, which spans about 6.3 kb and consists of five exons including three alternative first exons (1D, 1M, 1T) spliced onto common second and third exons. The LIF-D transcript encodes a protein of 202...
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