Mutational analysis does not support the existence of a putative tertiary structural element in the left terminal domain of Potato spindle tuber viroid.

Abstract excerpt

Comparative sequence analysis suggests that the left terminal domain of Potato spindle tuber viroid (PSTVd) and other large pospiviroids may assume a branched tertiary structure containing two pseudoknots. To search for evidence of such a structure in vivo, the nucleotide sequences proposed to interact were mutagenized, tomato seedlings were inoculated with mixtures of potentially infectious PSTVd RNA transcripts...

Topics

• Base Sequence
• Molecular Sequence Data
• Mutation
• Nucleic Acid Conformation
• Protein Structure, Tertiary
• Solanum tuberosum
• Viroids