Article
Identification of neutral mutants surrounding two naturally occurring variants of Potato spindle tuber viroid.
The Journal of general virology - 1 Mar 2003
Owens R A, Thompson S M, Kramer M
Abstract excerpt
Single point mutations in the pathogenicity domain of Potato spindle tuber viroid (PSTVd) can have a dramatic effect on disease expression, and only three substitutions are required for the spontaneous conversion of the type strain PSTVd-Intermediate to the rapidly replicating, highly pathogenic variant RG1 (Gruner et al., Virology 209, 60-69, 1995). To identify available evolutionary pathways linking these two...
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