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Article

Destabilization of potato spindle tuber viroid by mutations in the left terminal loop.

The Journal of general virology - 1 Jun 1997

Hu Y, Feldstein P A, Hammond J, Hammond R W, Bottino P J, Owens R A

Abstract excerpt

Infectivity studies with highly infectious RNA inocula generated by ribozyme cleavage were used to compare the biological properties of three apparently nonviable mutants of potato spindle tuber viroid (PSTVd). One of these mutants (PSTVd-P) contains three nucleotide substitutions in the left terminal loop, and mechanical inoculation of tomato seedlings with RNA transcripts at levels equivalent to 10(3)-10(5)...

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Identifiers

PMID: 9191908
DOI: 10.1099/0022-1317-78-6-1199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Destabilization of potato spindle tuber viroid by mutations in the left terminal loop.PMID 9191908Read ↗

Suppression of potato spindle tuber viroid replication and symptom expression by mutations which stabilize the pathogenicity domain.Semantic proximity Read ↗

A single nucleotide substitution converts potato spindle tuber viroid (PSTVd) from a noninfectious to an infectious RNA for nicotiana tabacum.Semantic proximity Read ↗

Mutational analysis does not support the existence of a putative tertiary structural element in the left terminal domain of Potato spindle tuber viroid.Semantic proximity Read ↗

Viability and genetic stability of potato spindle tuber viroid mutants with indels in specific loops of the rod-like secondary structure.Semantic proximity Read ↗

Agrobacterium-mediated inoculation of PSTVd cDNAs onto tomato reveals the biological effect of apparently lethal mutations.Semantic proximity Read ↗

Replication of Potato spindle tuber viroid in cultured cells of tobacco and Nicotiana benthamiana: the role of specific nucleotides in determining replication levels for host adaptation.Semantic proximity Read ↗

The genetic stability of potato spindle tuber viroid (PSTVd) molecular variants.Semantic proximity Read ↗

Viroid quasispecies revealed by deep sequencing.Semantic proximity Read ↗

RNA structural features responsible for potato spindle tuber viroid pathogenicity.Semantic proximity Read ↗

Identification of neutral mutants surrounding two naturally occurring variants of Potato spindle tuber viroid.Semantic proximity Read ↗

Functional analysis reveals G/U pairs critical for replication and trafficking of an infectious non-coding viroid RNA.Semantic proximity Read ↗

Genetic variability of potato spindle tuber viroid RNA replicon.Semantic proximity Read ↗

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