Article
High prevalence of glucose-6-phosphate dehydrogenase deficiency without gene mutation suggests a novel genetic mechanism predisposing to ketosis-prone diabetes.
The Journal of clinical endocrinology and metabolism - 1 Aug 2005
Sobngwi Eugene, Gautier Jean-François, Kevorkian Jean-Philippe, Villette Jean-Marie, Riveline Jean-Pierre, Zhang Sumei, Vexiau Patrick, Leal Suzanne M, Vaisse Christian, Mauvais-Jarvis Franck
Abstract excerpt
CONTEXT: Ketosis-prone diabetes (KPD) is mostly observed in males of West African descent and is characterized by phasic or permanent insulin dependence without apparent autoimmune process. OBJECTIVE: KPD subjects display a propensity to hyperglycemia-induced acute insulin deficiency, suggesting...
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