Article
Presence or absence of a known diabetic ketoacidosis precipitant defines distinct syndromes of "A-β+" ketosis-prone diabetes based on long-term β-cell function, human leukocyte antigen class II alleles, and sex predilection.
Metabolism: clinical and experimental - 1 Oct 2010
Nalini Ramaswami, Ozer Kerem, Maldonado Mario, Patel Sanjeet G, Hampe Christiane S, Guthikonda Anu, Villanueva Jesus, O'Brian Smith E, Gaur Lakshmi K, Balasubramanyam Ashok
Abstract excerpt
Ketosis-prone diabetes (KPD) is heterogeneous. Longitudinal follow-up revealed that patients with "A-β+" KPD (absent autoantibodies and preserved β-cell function) segregated into 2 subgroups with distinct evolution of β-cell function and glycemic control. Generalized linear analysis demonstrated...
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