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Article

Glucose-6-phosphate dehydrogenase activity and genetic variants in tunisian diabetic populations: A case-control study.

Journal of the National Medical Association - 1 Aug 2026

Amri Yessine, Othmani Mariem, Hannachi Nada, Tombari Sarra, Chelbi Siwar, Dridi Amira, Zmerli Nesrine, Hadj Fredj Sondess, Messaoud Taieb, Dabboubi Rym

Abstract excerpt

BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency, the most common X-linked enzymopathy, is highly prevalent in North Africa and impairs antioxidant defense by reducing NADPH production. Its relationship with diabetes mellitus (DM) remains unclear. AIMS: To assess G6PD enzymatic activity, determine the prevalence of G6PD deficiency, and identify common G6PD gene variants in Tunisian patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42135122
DOI: 10.1016/j.jnma.2026.04.007

Genes

G6PD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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