Article
Isoflurane-induced surgical tolerance mediated only in part by beta3-containing GABA(A) receptors.
European journal of pharmacology - 23 May 2005
Lambert Sachar, Arras Margarete, Vogt Kaspar E, Rudolph Uwe
Abstract excerpt
The targets which mediate the actions of the volatile general anaesthetic isoflurane are unknown. Based on pharmacological studies using GABA(A) receptor antagonists it has recently been suggested that GABA(A) receptors would not mediate the immobilizing action of isoflurane. Using the beta3(N265...
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