Article
Resistance to activated protein C caused by factor V Leiden mutation and orthotopic liver transplantation.
Transplantation - 27 May 2005
Loew Andreas, Jacob Dietmar, Neuhaus Peter, Riess Hanno
Abstract excerpt
BACKGROUND: Factor V (FV)-dependent resistance to activated protein C (APCR) is most likely caused by a point mutation in the FV gene, the so-called FV Leiden mutation (FV:Q506), which is a common risk factor predisposing to venous thromboembolism. Little is known about the role of FV:Q506 in recipients of human liver grafts and the significance of acquired APCR caused by orthotopic liver transplantation (OLT)....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
