Article

TMEM70 forms oligomeric scaffolds within mitochondrial cristae promoting <i>in situ</i> assembly of mammalian ATP synthase proton channel

2020-04-05

Abstract excerpt

Mitochondrial ATP-synthesis is catalyzed by a F1Fo-ATP synthase, an enzyme of dual genetic origin enriched at the edge of cristae where it plays a key role in their structure/stability. The enzyme’s biogenesis remains poorly understood, both from a mechanistic and a compartmentalization point of view. The present study provides novel molecular insights into this process through investigations on a human protein ca...

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Literature Corpus work: 5379673e-a984-5623-adb3-21fc59a14545
DOI: 10.1101/2020.04.03.023861

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