Influence of HLA antigens and OSAS in childhood: a preliminary report.

doi:10.1111/j.1365-2869.2005.00443.x

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Article

Influence of HLA antigens and OSAS in childhood: a preliminary report.

Journal of sleep research - 1 Jun 2005

Brunetti Luigia, Francavilla Ruggiero, Leonardo Miniello Vito, Leone Maddalena, Rana Michele, Colazzo Damiano, Logrillo Paolo, Favoino Biagio, Armenio Lucio

Abstract excerpt

Several studies have emphasized the role of familial factors and familial aggregation in increasing susceptibility to obstructive sleep apnea syndrome (OSAS); the aim of the present study was to investigate the possible influence of human leukocyte antigen (HLA) in the development of sleep disordered breathing and OSAS of children. Between January 2000 and January 2003, all the 370 children [193 males; median...

Topics

Child
Child, Preschool
Female
Gene Frequency
Genetic Predisposition to Disease
Genetics, Population
Histocompatibility Antigens Class I
Humans
Infant
Italy
Male
Odds Ratio
Polymerase Chain Reaction
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 15910513
DOI: 10.1111/j.1365-2869.2005.00443.x

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Sleep Apnea, Obstructive

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