Article
TNF-α gene polymorphisms and excessive daytime sleepiness in pediatric obstructive sleep apnea.
The Journal of pediatrics - 1 Jan 2011
Khalyfa Abdelnaby, Serpero Laura D, Kheirandish-Gozal Leila, Capdevila Oscar Sans, Gozal David
Abstract excerpt
OBJECTIVE: To assess sleepiness, TNF-α plasma levels, and genomic variance in the TNF-α gene in children with obstructive sleep apnea (OSA). STUDY DESIGN: Children being evaluated for OSA (n = 60) and matched control children (n = 80) were assessed with a modified Epworth Sleepiness Scale questionnaire and underwent a blood draw the morning after nocturnal polysomnography. TNF-α plasma concentrations were assayed...
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