Article
Donor CD31 genotype and its association with acute graft-versus-host disease in HLA identical sibling stem cell transplantation.
Bone marrow transplantation - 1 Jul 2005
Goodman R S, Ewing J, Evans P C, Craig J, Poulton K, Dyer P A, Marcus R E, Taylor C J
Abstract excerpt
CD31 gene polymorphisms are implicated in the pathogenesis of graft-versus-host disease (GvHD) following haematopoietic stem cell transplantation (HST). We investigated the influence of CD31 genotype on the incidence of GvHD following HST from an human leukocyte antigen (HLA)-identical sibling donor. Donor and recipient CD31 codons 125, 563 and 670 DNA polymorphisms were determined in 85 cases of HLA identical...
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