Article
Polymorphism of adhesion molecule CD31 is not a significant risk factor for graft-versus-host disease.
Blood - 15 Dec 1996
Nichols W C, Antin J H, Lunetta K L, Terry V H, Hertel C E, Wheatley M A, Arnold N D, Siemieniak D R, Boehnke M, Ginsburg D
Abstract excerpt
Mismatch between bone marrow transplant (BMT) patient and donor for an amino acid polymorphism within the adhesion molecule CD31 has recently been reported to increase risk for the development of graft-versus-host disease (GVHD). We further examined this association in a larger series of 301 BMT patients (227 with grade III/IV GVHD and 74 with grade 0 GVHD) and their HLA-identical sibling donors. CD31 genotypes...
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