A Newly Discovered Mycobacterial Pathogen Isolated from Laboratory Colonies of <i>Xenopus</i> Species with Lethal Infections Produces a Novel Form of Mycolactone, the <i>Mycobacterium ulcerans</i> Macrolide Toxin

Abstract excerpt

Mycobacterium ulcerans, the causative agent of Buruli ulcer, produces a macrolide toxin, mycolactone A/B, which is thought to play a major role in virulence. A disease similar to Buruli ulcer recently appeared in United States frog colonies following importation of the West African frog, Xenopus tropicalis. The taxonomic position of the frog pathogen has not been fully elucidated, but this organism, tentatively...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Infectious Diseases and Mycology
• Share to Mycobacterium research and diagnosis