Evolution of <i>Mycobacterium ulcerans</i> and Other Mycolactone-Producing Mycobacteria from a Common <i>Mycobacterium marinum</i> Progenitor

Abstract excerpt

It had been assumed that production of the cytotoxic polyketide mycolactone was strictly associated with Mycobacterium ulcerans, the causative agent of Buruli ulcer. However, a recent study has uncovered a broader distribution of mycolactone-producing mycobacteria (MPM) that includes mycobacteria cultured from diseased fish and frogs in the United States and from diseased fish in the Red and Mediterranean Seas....

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