Article
Influence of maternal-fetal histocompatibility and MHC zygosity on maternal microchimerism.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 2005
Kaplan Joseph, Land Susan
Abstract excerpt
To investigate the relationship between maternal-fetal histocompatibility and maternal microchimerism, we developed a sensitive quantitative PCR assay for the neomycin resistance gene (neoR), and, in a mouse model system, used neoR as a noninherited maternal allele marker of maternal cells to detect and quantitate maternal microchimerism in tissues of neoR(-/-) N2 backcross progeny of (neoR(+/-))F(1) females...
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