Article
Maternal and sibling microchimerism in twins and triplets discordant for neonatal lupus syndrome-congenital heart block.
Rheumatology (Oxford, England) - 1 Feb 2005
Stevens A M, Hermes H M, Lambert N C, Nelson J L, Meroni P L, Cimaz R
Abstract excerpt
OBJECTIVE: Neonatal lupus syndrome-congenital heart block (NLS-CHB) is an acquired autoimmune disease in which maternal autoantibodies are necessary but not sufficient for disease. Maternal myocardial cells have been found in the hearts of patients with NLS-CHB, suggesting that maternal microchimerism may also play a role. In this study we asked whether levels of microchimerism in the blood are associated with...
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