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Article

Endothelial nitric oxide synthase -786T>C, but not 894G>T and 4a4b, polymorphism influences plasma homocysteine concentrations in persons with normal vitamin status.

Clinical chemistry - 1 Jul 2005

Fatini Cinzia, Sofi Francesco, Gori Anna Maria, Sticchi Elena, Marcucci Rossella, Lenti Meri, Casini Alessandro, Surrenti Calogero, Abbate Rosanna, Gensini Gian Franco

Abstract excerpt

BACKGROUND: Nitric oxide (NO) plays a relevant role in various events during atherogenesis. In vitro data suggest that NO may modulate homocysteine (Hcy) concentrations. The aim of this study was to investigate the role of endothelial nitric oxide synthase (eNOS) -786T>C, 894G>T, and 4a4b polymorphisms in influencing Hcy concentrations. METHODS: Blood samples were obtained from 1287 unrelated persons. Plasma Hcy...

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Source

Identifiers

PMID: 15905312
DOI: 10.1373/clinchem.2005.048850

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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