Article
Progeria: a human-disease model of accelerated aging.
The American journal of clinical nutrition - 1 Jun 1992
Brown W T
Abstract excerpt
Progeria is a rare genetic disease with striking features that resemble accelerated aging. The inheritance pattern, paternal age effect, and lack of consanguinity argue that it is due to a sporadic dominant mutation. We have observed elevated levels of hyaluronic acid (HA) excretion in progeria p...
Topics
- Basal Metabolism
- Growth Hormone
- Humans
- Hyaluronic Acid
- Insulin-Like Growth Factor I
- Mutation
- Progeria
- Werner Syndrome
