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Article

Progeria: a human-disease model of accelerated aging.

The American journal of clinical nutrition - 1 Jun 1992

Brown W T

Abstract excerpt

Progeria is a rare genetic disease with striking features that resemble accelerated aging. The inheritance pattern, paternal age effect, and lack of consanguinity argue that it is due to a sporadic dominant mutation. We have observed elevated levels of hyaluronic acid (HA) excretion in progeria patients. In several progeria patients we observed normal levels of growth hormone (GH) but very low levels of...

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PMID: 1590260
DOI: 10.1093/ajcn/55.6.1222S

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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