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Disease Progression in Hutchinson-Gilford Progeria Syndrome: Impact on Growth and Development

1 Oct 2007

Abstract excerpt

OBJECTIVES: Hutchinson-Gilford progeria syndrome is a rare and uniformly fatal segmental "premature aging" disease that affects a variety of organ systems. We sought to more clearly define the bone and weight abnormalities in patients with progeria as potential outcome parameters for prospective clinical trials. PATIENTS AND METHODS: We collected and analyzed longitudinal medical information, both retrospectively...

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PMID: 17908770
DOI: 10.1542/peds.2007-1357

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