Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GCN2 Kinase in T Cells Mediates Proliferative Arrest and Anergy Induction in Response to Indoleamine 2,3-Dioxygenase

1 May 2005

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder and Treatment
Share to Endoplasmic Reticulum Stress and Disease
Share to Tryptophan and brain disorders

Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 15894280
DOI: 10.1016/j.immuni.2005.03.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GCN2 Kinase in T Cells Mediates Proliferative Arrest and Anergy Induction in Response to Indoleamine 2,3-DioxygenasePMID 15894280Read ↗

Itaconate: A key regulator of immune responses and potential therapeutic target for autoimmune and inflammatory diseasesSemantic proximity Read ↗

S-2HG is an immunometabolite that shapes the T-cell response.Semantic proximity Read ↗

A non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferationSemantic proximity Read ↗

The gene related to anergy in lymphocytes, an E3 ubiquitin ligase, is necessary for anergy induction in CD4 T cells.Semantic proximity Read ↗

NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia.Semantic proximity Read ↗

Differential CTLA-4 expression in human CD4+ versus CD8+ T cells is associated with increased NFAT1 and inhibition of CD4+ proliferationSemantic proximity Read ↗

p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytesSemantic proximity Read ↗

Early Growth Response Gene-2, a Zinc-Finger Transcription Factor, Is Required for Full Induction of Clonal Anergy in CD4+ T CellsSemantic proximity Read ↗

Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytesSemantic proximity Read ↗

Human immunodeficiency virus type 1 clade B and C Tat differentially induce indoleamine 2,3-dioxygenase and serotonin in immature dendritic cells: Implications for neuroAIDSSemantic proximity Read ↗

T-cell anergy: from phenotype to genotype and back.Semantic proximity Read ↗

The amino acid sensor general control nonderepressible 2 (GCN2) controls TH9 cells and allergic airway inflammationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.