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Article

Association of von Willebrand factor activity with ACE I/D and MTHFR C677T polymorphisms in migraine.

Cephalalgia : an international journal of headache - 1 Sept 2009

Tietjen G E, Herial N A, Utley C, White L, Yerga-Woolwine S, Joe B

Abstract excerpt

Angiotensin-converting enzyme (ACE) insertion (I)/deletion (D) and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms are linked to endothelial dysfunction and to cerebral white matter lesions. Objectives of this study were to determine if ACE and MTHFR gene polymorphisms are associated with von Willebrand factor (vWF) activity, an endothelial dysfunction marker, and with a distinct headache...

Read the complete abstract on PubMed

Topics

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Share to Endothelium, Vascular
Share to Methylenetetrahydrofolate Reductase (NADPH2)

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Migraine Disorders

Share to Peptidyl-Dipeptidase A

Share to Polymorphism, Genetic

Share to Risk Factors

Share to von Willebrand Factor

Share to Young Adult

Source

Identifiers

PMID: 19298544
DOI: 10.1111/j.1468-2982.2008.01824.x

Genes

ACE
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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