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RNA and Protein Requirements for Incorporation of the Pol Protein into Foamy Virus Particles

12 May 2005

Abstract excerpt

Foamy viruses (FVs) generate their Pol protein precursor molecule independently of the Gag protein from a spliced mRNA. This mode of expression raises the question of the mechanism of Pol protein incorporation into the viral particle (capsid). We previously showed that the packaging of (pre)genomic RNA is essential for Pol encapsidation (M. Heinkelein, C. Leurs, M. Rammling, K. Peters, H. Hanenberg, and A....

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Identifiers

PMID: 15890940
DOI: 10.1128/jvi.79.11.7005-7013.2005

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