Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Orthoretroviral-like prototype foamy virus gag-pol expression is compatible with viral replication

15 Aug 2011

Abstract excerpt

BACKGROUND: Foamy viruses (FVs) unlike orthoretroviruses express Pol as a separate precursor protein and not as a Gag-Pol fusion protein. A unique packaging strategy, involving recognition of briding viral RNA by both Pol precursor and Gag as well as potential Gag-Pol protein interactions, ensures Pol particle encapsidation. RESULTS: Several Prototype FV (PFV) Gag-Pol fusion protein constructs were generated to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to Mosquito-borne diseases and control
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21843316
DOI: 10.1186/1742-4690-8-66

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Orthoretroviral-like prototype foamy virus gag-pol expression is compatible with viral replicationPMID 21843316Read ↗

Mutagenesis of N-terminal residues of feline foamy virus Gag reveals entirely distinct functions during capsid formation, particle assembly, Gag processing and budding.Semantic proximity Read ↗

Novel Functions of Prototype Foamy Virus Gag Glycine- Arginine-Rich Boxes in Reverse Transcription and Particle MorphogenesisSemantic proximity Read ↗

A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and CapsidSemantic proximity Read ↗

Analysis of Prototype Foamy Virus particle-host cell interaction with autofluorescent retroviral particlesSemantic proximity Read ↗

Characterization of Prototype Foamy Virus Gag Late Assembly Domain Motifs and Their Role in Particle Egress and InfectivitySemantic proximity Read ↗

Foamy Virus Budding and ReleaseSemantic proximity Read ↗

RNA and Protein Requirements for Incorporation of the Pol Protein into Foamy Virus ParticlesSemantic proximity Read ↗

Pregenomic RNA Is Required for Efficient Incorporation of Pol Polyprotein into Foamy Virus CapsidsSemantic proximity Read ↗

Improved Primate Foamy Virus Vectors and Packaging ConstructsSemantic proximity Read ↗

Correct capsid assembly mediated by a conserved YXXLGL motif in prototype foamy virus Gag is essential for infectivity and reverse transcription of the viral genome.Semantic proximity Read ↗

Foamy virus reverse transcriptase is expressed independently from the Gag protein.Semantic proximity Read ↗

The human foamy virus pol gene is expressed as a Pro-Pol polyprotein and not as a Gag-Pol fusion proteinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.