Article
Germline mutations of the MYH gene in Japanese patients with multiple colorectal adenomas.
Mutation research - 15 Oct 2005
Miyaki Michiko, Iijima Takeru, Yamaguchi Tatsuro, Hishima Tsunekazu, Tamura Kazuo, Utsunomiya Joji, Mori Takeo
Abstract excerpt
Germline mutations of the MYH gene have been revealed to associate with the recessive inheritance of multiple colorectal adenomas in Caucasian population. However, MYH mutations in Japanese patients have not yet been clarified. In an assessment of MYH mutations, we examined 35 Japanese patients with multiple colorectal adenomas who had neither dominant inheritance of colorectal tumors, nor germline APC mutations....
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