Article
The Cdc14p phosphatase affects late cell-cycle events and morphogenesis in Candida albicans.
Journal of cell science - 15 Mar 2006
Clemente-Blanco Andrés, González-Novo Alberto, Machín Félix, Caballero-Lima David, Aragón Luis, Sánchez Miguel, de Aldana Carlos R Vázquez, Jiménez Javier, Correa-Bordes Jaime
Abstract excerpt
We have characterized the CDC14 gene, which encodes a dual-specificity protein phosphatase in Candida albicans, and demonstrated that its deletion results in defects in cell separation, mitotic exit and morphogenesis. The C. albicans cdc14delta mutants formed large aggregates of cells that resembled those found in ace2-null strains. In cdc14delta cells, expression of Ace2p target genes was reduced and Ace2p did...
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