Article
A G1 cyclin is necessary for maintenance of filamentous growth in Candida albicans.
Molecular and cellular biology - 1 Jun 1999
Loeb J D, Sepulveda-Becerra M, Hazan I, Liu H
Abstract excerpt
Candida albicans undergoes a dramatic morphological transition in response to various growth conditions. This ability to switch from a yeast form to a hyphal form is required for its pathogenicity. The intractability of Candida to traditional genetic approaches has hampered the study of the molecular mechanism governing this developmental switch. Our approach is to use the more genetically tractable yeast...
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