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Article

Failure to replicate previously reported genetic associations with sporadic temporal lobe epilepsy: where to from here?

Brain : a journal of neurology - 1 Aug 2005

Cavalleri Gianpiero L, Lynch John M, Depondt Chantal, Burley Mari-Wyn, Wood Nicholas W, Sisodiya Sanjay M, Goldstein David B

Abstract excerpt

Temporal lobe epilepsy (TLE), traditionally thought to develop largely due to environmental factors, has recently become the focus of association studies in an effort to determine genetic risk factors. Here we examine all previous claims of association of genetic polymorphisms with TLE by attempting replication in a cohort of 339 TLE patients of European origin. We also examine if these variants contribute to...

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Identifiers

PMID: 15888540
DOI: 10.1093/brain/awh524

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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