Article
Apolipoprotein E polymorphisms and the risk of nonlesional temporal lobe epilepsy.
Epilepsia - 1 Dec 1999
Gambardella A, Aguglia U, Cittadella R, Romeo N, Sibilia G, LePiane E, Messina D, Manna I, Oliveri R L, Zappia M, Quattrone A
Abstract excerpt
PURPOSE: To evaluate whether the inheritance of the apolipoprotein E (ApoE) epsilon4 allele is a risk factor for nonlesional temporal lobe epilepsy (TLE), and to determine whether the newly described -491 A/T ApoE polymorphism may independently affect the risk of nonlesional TLE. METHODS: The study group consisted of 63 patients (35 women and 28 men; age at onset of epilepsy, 30.6 +/- 19.6 years; mean (+/-SD)....
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