Article
Vitamin D receptor Fok1 polymorphisms affect calcium absorption, kinetics, and bone mineralization rates during puberty.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 2005
Abrams Steven A, Griffin Ian J, Hawthorne Keli M, Chen Zhensheng, Gunn Sheila K, Wilde Margaret, Darlington Gretchen, Shypailo Roman J, Ellis Kenneth J
Abstract excerpt
UNLABELLED: Few studies of the VDR polymorphisms have looked at calcium metabolism or long-term effects. We measured bone mineralization and calcium metabolic parameters longitudinally in a group of 99 adolescents. We found a significant relationship between calcium absorption and skeletal calcium accretion and the Fok1, but not other VDR or related, genetic polymorphisms. It seems that the Fok1 polymorphism...
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