Article
Vitamin D receptor start codon polymorphism ( FokI) is related to bone mineral density in healthy adolescent boys.
Journal of bone and mineral metabolism - 1 Jan 2003
Strandberg Sara, Nordström Peter, Lorentzon Ronny, Lorentzon Mattias
Abstract excerpt
Peak bone mass is considered a major determinant in the emergence of osteoporosis and is mainly genetically regulated. Several genes have been investigated, among them the vitamin D receptor ( VDR) gene. A single-nucleotide polymorphism (defined by the endonuclease FokI) located in the start codon of the VDR creates the alleles F and f, resulting in different proteins. A number of previous studies have proved the...
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